Megaloblastic Anaemia of Pregnancy and the Puerperium

Megaloblastic anaemia of pregnancy and the puerperium.

An account of 335 cases of megaloblastic anaemia of pregnancy and the puerperium.

The incidence of megaloblastic anaemia in pregnancy and the puerperium in north Staffordshire has steadily declined as a result of prophylaxis with folic acid. In the presence of advanced folic acid deficiency and with a florid megaloblastic marrow, the anaemia is usually severe, but in many patients the disease is relatively mild and the degree of anaemia is determined more by blood loss or as...

A leukaemoid blood picture in megaloblastic anaemia of the puerperium.

Case Reports Case 1.-Aged 32. Two previous pregnancies normal. Tiredness, swelling of ankles during last three weeks of third pregnancy. Labour normal, no undue blood loss. Admitted to hospital 10 days after delivery. Treatment during Pregnancy.-None. During the five days before admission she had taken eight capsules of a compound haematinic, which did not contain vitamin B12 but included a min...

Minimal criteria for the diagnosis of megaloblastic anaemia of pregnancy.

The routine examination of buffy coat films is a valuable diagnostic aid to screening large numbers of specimens of blood and is applicable to hospital and general practice, provided that a bottle of sequestrinated venous blood can be examined in the laboratory within 24 hours.The diagnosis of folic-acid deficiency anaemia of pregnancy can be made, in many cases, before the appearance of megalo...

Pigmentation in megaloblastic anaemia associated with pregnancy and lactation.

Generalized skin pigmentation in five African women with megaloblastic anaemia in the postnatal period was associated with low serum folate levels, as distinct from vitamin B(12) deficiency. It is suggested that the occurrence of pigmentation in both folate and vitamin B(12) deficiency may reflect a common abnormality of metabolism.